Core Nutritionals HMB Product Information
HMB is suggested to:
- Attenuate the rate
of muscle protein breakdown.*
- Reduce muscle
damage during periods of strenuous exercise.*
- Increase power
output during explosive movements.*
HMB (otherwise known as β-Hydroxy β-Methylbutyrate) is like
the pretty girl who used to sit across from you in biology: sexy, mysterious,
but most of all, pretty complex and little understood. And like that girl, the
more you actually understand about this fascinating compound, the more you will
like it.
HMB burst onto the bodybuilding market in the early 1990’s,
and every supplement company and their brother marketed the compound so heavily
it gained a reputation as snake oil. The reviews were so varied that HMB was
almost relegated to the dustbin of supplement history.
Times have changed, however, and people have once again
begun to realize that, when used properly at an effective serving, HMB’s
positive contributions to a muscle-sparing environment are impossible to
overlook.*
Science:
HMB (β-Hydroxy β-Methylbutyrate) is an endogenous metabolite
of leucine consumption, being derived from its parent amino acid through two
steps of enzymatic conversion. In total, approximately 5% of leucine by weight
of consumption is converted into HMB.
Once converted, HMB has been demonstrated to possess several
interesting effects. In cellular assays, HMB was suggested to increase the rate
of skeletal protein synthesis through the same mechanism as its parent
compound, leucine – the all-important mTOR-P13K pathway that regulates the
majority of muscle protein synthesis in vivo.* This mechanism has also
translated into practical benefits to human muscle, as various trials have
demonstrated HMB to slow the rate of skeletal muscle breakdown, increase power
output over both acute (short) and chronic (long-term) trials, as well as
mitigating muscle damage during high-intensity exercise.*
Supplement Facts
Serving Size: 1 scoop (1000 mg)
Servings Per Container: 90
Amount Per Serving %
Daily Value
Calcium (From Calcium β-Hydroxy β-Methylbutyrate) 130 mg 13%†
β-Hydroxy β-Methylbutyrate (HMB) 1,000 mg †
(As Calcium β-Hydroxy β-Methylbutyrate Monohydrate)
† Daily value not established. Percent Daily Values are
based on a 2,000 calorie diet.
Directions For HMB: Consume 1 scoop (1000 mg) three times
per day, preferably with food. For best results, take one serving 30-60 minutes
before your workout.
Warnings: Not intended for use by pregnant or nursing women
or persons under the age of 18. If you are taking any medications or have any
medical condition, consult your doctor before use. Discontinue use and consult
your doctor if any adverse reactions occur. Discontinue use 2 weeks prior to
surgery. Do not exceed recommended serving. Do not use if safety seal is broken
or missing. Keep out of the reach of children. Store in a cool, dry place.