| | |
|
| |
| | |
|
|
MuscleMeds Hexaghen 56 tabs
|
Retail Price: $79.99
Our Price: $45.99
|
MuscleMeds Hexaghen Product Information
The development of HEXAGHEN, the first ever orally effective
maximum threshold IGF-1 activator, is going to help breed a new
generation of monstrous bodybuilders. Scientists have proclaimed
IGF-1 to be the "new holy grail to muscle growth". It poses
extremely actions and is the critical mediator of muscle growth
as it stimulates both the differentiation and proliferation of
myoblasts (muscle cells). In general terminology, this means that IGF-1
has the unique ability to actually increase not only the size but also
the number of muscle cells. IGF-1 produced in the body also enhances
muscle growth by increasing amino acid uptake and protein synthesis.
With the discovery of IGF-1's powerful effects, world-class
bodybuilders quickly sought out a means to directly increase IGF-1
through recombinant IGF-1 injections.
Now, through the development of HEXAGHEN, you can experience
the extreme promoting effects by boosting your IGF-1 levels.
HEXAGHEN's maximum threshold IGF-1 output can help promote muscle cell hyperplasia and stimulate muscle cell growth. Based on
independent research studies, IGF-1 has been shown to increase a very
powerful influence on muscle growth.
HEXAGHEN's efficacy is made possible through the utilization
of a unique combination of highly specialized actives, which includes:
GHRP-2 Hexapeptide Acetate, cis -4, 17(20)-pregnadiene-3,16-dione, and
trans-4, 17(20)-pregnadiene-3,16-dione. These advanced compounds are
administered in FastSorb tablet delivery. The FastSorb tablet provides
optimum delivery, which is critical for these potent yet fragile
compounds to be absorbed directly into the bloodstream, bypass the
gastrointestinal tract and first-pass metabolism in the liver thereby
preserving their activity and effectiveness as an IGF-1 Activator.
HEXAGHEN is clearly the most exciting muscle-building breakthrough on
the bodybuilding circuit today.
THE SCIENCE BEHIND HEXAGHEN
DESCRIPTION:
HEXAGHEN FastSorb tablets belong to a new class of orally
effective IGF-1 (Insulin-Like Growth Factor-1) stimulating compounds.
HEXAGHEN utilizes a FastSorb delivery system for rapid absorption and
maximum bioavailability.
ACTIVE COMPOUNDS:
HEXAGHEN FastSorb tablets for oral administration contain IGF-1 Optimizing synergistic compounds:
- GHRP-2 Hexapeptide Acetate
- cis -4, 17(20)-pregnadiene-3,16-dione
- trans-4, 17(20)-pregnadiene-3,16-dione
THE SCIENCE OF INSULIN-LIKE GROWTH FACTOR-1 (IGF-1)
IGF-1 produced in the body possess some unique characteristics
and is one of the most potent natural activators of the AKT signaling
pathway, a stimulator of cell growth and multiplication. Attention was
first turned to IGF-1 when scientists researching growth hormone
discovered that Growth Hormone (GH) influence on IGF-1 production was
the responsible factor for the effects associated with growth
hormone administration and natural elevation in the body. In fact, while
GH has direct fat burning effects as it metabolizes stored body fat,
its muscle building effects are actually attributed to its effects on
increasing IGF-1 levels. Therefore, it is IGF-1 and not GH that directly
mediates muscle cell hyperplasia and muscle growth at the cellular
level. IGF-1 is thought to be the critical mediator as it stimulates
both the differentiation and proliferation of myoblasts (muscle cells),
resulting in muscle growth. IGF-1 also enhances muscle growth by
increasing amino acid uptake and protein synthesis.
IGF-1 is an important peptide hormone that is involved in
regulating growth and development of muscle tissue. Its primary action
is mediated by binding to specific IGF-1 receptors present on many cell
types in many tissues. The free form IGF-1 fraction is highly bio-active
in comparison to the IGF-1 bound to IGF Binding Proteins (IGFBPs).
IGF-1 is the principal hormonal mediator of growth in the body. In the
cascade of biochemical events leading to a surge in IGF-1 production and
levels, HEXAGHEN stimulated growth hormone is metabolized by the liver
and potentiates the synthesis and secretion of IGF-1.
Muscle tissue has an abundance of IGF-1 receptors. When serum
IGF-1 binds to these receptor sites on muscle tissue, it stimulates the
following actions and growth processes in humans, including
increasing the number and size of muscle cells:
- Regulates cell growth and development
- Regulates cellular DNA synthesis
- Mediates muscle cell hyperplasia and muscle fiber development initiation and maturation.
- Stimulates the growth and size of muscle cells
- Stimulates glucose uptake by myoblasts (muscle precursor cells),
which fuels their growth and development into muscle fiber cells
- Increases muscle cell uptake of amino acids, uses as building blocks of muscle protein molecules
- Increases nitrogen retention and a greater food conversion efficiency
- Reduces nitrogen excretion
- Improves wound healing
- Stimulates muscle protein synthesis
- Preferentially stimulates the growth of lean tissue
- Stimulates mitogenic (cell replication) activities that lead to an increased number of muscle cells in the body
- Vital for muscle repair and regeneration
- Causes improvements in body composition, demonstrating a decrease in body fat mass and a profound increase in lean body mass
The relationship within the endocrine/IGF-1 axis is a complex
system. Scientists have recently identified other factors that play a
critical role in effecting IGF-1 levels. Approximately 98% of IGF-1 is
bound to one of several insulin-like growth factor binding proteins
(IGFBP). IGFBP-3, the most abundant protein, accounts for 80% of all
IGF-1 binding. Research has demonstrated that reducing IGF-1 binding
proteins and maintaining higher levels of free IGF-1 is correlated to
improved effects and muscle development.
As reported in independent research journals, thyroid
function is also associated with enhancing IGF-1 bio-active tissue
levels and further increasing the rate of protein synthesis. Therefore,
as IGF-1 levels are increased, a series of negative feedback controls
involving the thyroid endocrine axis are triggered to keep IGF-1 levels
within a narrow physiological range; not too high and not too low. From
examining the relationships between GH, IGF-1 production, IGF-1 levels,
free IGF-1, IGFBP, and thyroid function, MuscleMeds researchers
addressed
this correlation between IGF-1 production and bio-effectiveness related to thyroid stimulation. HEXAGHEN's synergistic thyroid
involvement is designed to help sustain higher total and free IGF-1
levels for longer periods of time, thereby extending the overall desired
IGF-1 effects.
Research and Development
The muscle building effects of IGF-1 have been well known and
medically documented for years. But, the controlling factors regulating
the body's natural output have challenged researchers. Synthetic IGF-1
has been produced by major biotech pharmaceutical companies on a large
scale using recombinant DNA technology. These synthetic forms must be
administered via injection dosing. The development of an orally
effective IGF-1 enhancing compound has long been a major global
objective of biotechnologists.
After years of extensive research and laboratory analysis, MuscleMeds researchers discovered a unique IGF-1 stimulating hexapeptide
(GHRP-2 Hexapeptide Acetate). Due to its long hexapeptide
structure, the development of an effective oral dosage form for GHRP-2
Hexapeptide posed some biotechnical challenges. Conventional oral dosing
(such as tablets, capsules, liquids and softgels) was ineffective due
to the gastrointestinal destruction of the GHRP-2 hexapeptide. As with
other peptide substances, GHRP-2 hexapetide is subject to destruction
(breakdown) in the gastrointestinal system, which eliminates the
effectiveness and ability to reach the hypothalamus-pituitary axis. In
order to create a product that is suitable for oral administration of
the HEXAGHEN GHRP-2 Hexapeptide acetate, MuscleMeds scientists employed
the utilization of their proprietary FastSorb delivery system
technology.
As a result of this researched based product development
effort, HEXAGHEN features a unique IGF-1 Optimizing Complex. HEXAGHEN's
novel ingredient composition and proprietary liposomal delivery system
is designed to stabilize the bioactives for rapid and high levels of
absorption directly into the blood stream primarily through buccal
cavity (mouth) absorption. Oral mucosal dosage delivery (transmucosally)
is an alternative method of systemic nutrient delivery, which offers
several advantages as the oral mucosa is highly vascularised with
absorptive abilities. Therefore, HEXAGHEN's active compounds are
absorbed through the oral mucosa directly enter the bloodstream,
bypassing the gastrointestinal tract and first-pass metabolism in the
liver. This improves the bioeffectiveness of delivery into the body, to
trigger a series of endocrine medicated events: HEXAGHEN stimulates GH
and IGF-1 levels and supports thyroid function for maximum effects.
Nutrition Facts:
Serving Size: 2 Tablets
Servings Per Container: 28
Amount Per Serving:
Hexaghen 12.6mg
[Patent Pending IGF-1 Complex Of: Ketonic Isomers(Cis And Trans-4, 17(20)-Pregnadiene-3,16-Dione), GHRP-2 Hexapeptide Acetate]
Note: Manufacturers continually change product specifications. While
we try our best to keep product descriptions up to date, they do not
necessarily reflect the latest information available from the
manufacturer. We are not responsible for incorrect or outdated product
descriptions and/or images.
These statements have not been evaluated by the Food and Drug
Administration. This product is not intended to diagnose, treat, cure,
or prevent any disease.
|
Product Reviews
|
|
|